Asian Journal of Research in Chemistry

F. Nikhat ¹, D. Satyanarayana ¹, M. G. Purohit ¹, Bharat ¹, A. Moid ¹

Affiliations
1 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, IN

Abstract

Syzygium cuminii (L) skeel commonly known as 'jamun' is widely used in Indian folk medicine for the treatment of diabetes Mellitus. The present study an attempt has been made to produce a complete analytical and chemical profile of the isolated constituents of ischolar_main's of syzygium cuminii(L) skeel . The pharmacological and pharmaceutical work is going on in our laboratory.

Keywords

Syzygium cuminii (L) skeel, Constituents, Diabetes.

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F. Nikhat ¹, D. Satyanarayana ¹

Affiliations
1 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy Gulbarga-585201, IN

Abstract

The present study depends on the collection of plant material authentication, extraction, isolation, characterization and toxicity study. The aim of the present work is to isolate the pure plant material in a signal form to carry out the pharmacological activity.

Keywords

Authentication, Extraction, Isolation, Characterization, Toxicity.

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Akash P. Dahake ¹, D. Satyanarayana ¹, Arun B. Joshi ¹, K. S. Chandarshekhar ¹, Himanshu Joshi ¹

Affiliations
1 Dept. of Pharmacognosy, N.G.S.M Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore-574160, IN

Abstract

The investigation was carried out to study the antihyperglycemic effects of ethanolic extract of Anacardium occidentale leaves in normal, glucose loaded and alloxan induced diabetic rats. The ethanolic extract of A. occidentale at a dose of 100, 200, 400 mg/kg of body weight (p.o) and standard drug glibenclamide 500 μg/kg, in all three animal models. The serum glucose level was determined at 0, 4, 8 and 12 days after treatment. The extract exhibited significant hypoglycemic activity in all three animal models when compared with a standard antidiabetic agent Glibenclamide. The hypoglycemia produced by the extract may be due to increased uptake of glucose at tissue level and or increase in pancreatic β-cell function or due to inhibition of intestinal glucose absorption of glucose. The study indicated that the ethanolic extract of Anacardium occidentale is a potential antidiabetic agent and lends scientific support for it’s use in folk medicine.

Keywords

Anacardium occidentale, Diaebetes, Alloxan.

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